產(chǎn)品名稱：活性氧Lipofermata，CAS No. 297180-15-5

產(chǎn)地：西安

規(guī)格：1mg 5mg 10mg

純度：99%

用途：僅用于科研

狀態(tài)：固體/粉末

儲(chǔ)藏條件：冷藏-20℃

溫馨提示：僅用于科研，不能用于人體實(shí)驗(yàn)！

說明：提供使用說明，核磁圖譜，包裝，價(jià)格，產(chǎn)地，制備方法，應(yīng)用，穩(wěn)定性，溶解度，簡單合成等各種信息　　

Lipofermata is an inhibitor of fatty acid transport (IC50 = 4.84 μM in Caco-2 cells).1 It inhibits uptake of long- and very long-chain, but not medium-chain, fatty acids in mmC2C12, rnINS-1E, Caco-2, and HepG2 cells (IC50s = 3-6 μM).2 Lipofermata inhibits induction of BiP and CHOP, apoptosis, and lipid droplet accumulation, as well as reduces production of reactive oxygen species (ROS) and reverses decreases in glutathione (GSH) levels induced by palmitate in HepG2 and INS-1E cells. In vivo, lipofermata (500 mg/kg) inhibits absorption of 13C-oleate in mice.

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編輯：XAQYBIO HAO，2023年4月15日。