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活性氧Pargyline (hydrochloride),CAS No. 306-07-0

2023-04-19 15:16 作者:齊岳hao  | 我要投稿

產(chǎn)品名稱:活性氧Pargyline (hydrochloride),CAS No. 306-07-0

產(chǎn)地:西安

規(guī)格:1mg 5mg 10mg

純度:99%

用途:僅用于科研

狀態(tài):固體/粉末

儲藏條件:冷藏-20℃

溫馨提示:僅用于科研,不能用于人體實驗!

說明:提供使用說明,核磁圖譜,包裝,價格,產(chǎn)地,制備方法,應用,穩(wěn)定性,溶解度,簡單合成等各種信息  

Pargyline is an irreversible inhibitor of monoamine oxidase (MAO; Kis = 15 and 1.8 μM for MAO-A and MAO-B, respectively).1 At 10 mg/kg i.v., pargyline induces a moderate decrease of systolic blood pressure in unanaesthetized hypertensive rats but not normotensive WKR or Sprague-Dawley rats.2 The correlation between the fall of blood pressure and the inhibition of brain MAO suggests that the accumulation of amine in brain is responsible for the fall in pressure.3 Reactive oxygen species-mediated monocyte hypertrophy is prevented by pargyline at a concentration of 10 μM.4 Formulations containing pargyline have been used to treat moderate hypertension.4,5

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編輯:XAQYBIO HAO,2023年4月15日。

活性氧Pargyline (hydrochloride),CAS No. 306-07-0的評論 (共 條)

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