品名

三硫化銻; 三硫化二銻; 硫化亞銻; 銻橙; 銻朱; Antimony Trisulfide; Antimony glance; Antimony orange; Stibnite; CAS：1345-04-6

廣分質(zhì)檢院電話：131-1271-9619? 周經(jīng)理? 微信同手機(jī)號(hào)

理化性質(zhì)

灰色有光澤結(jié)晶塊、黑灰色粉末、紅色變體、黑色斜方晶體。分子式Sb2S3。分子量339.72。相對(duì)密度4.12。熔點(diǎn)550℃。沸點(diǎn)約1150℃。不溶于水; 溶于濃鹽酸、硫化銨和硫化鈉溶液。在鹽酸中產(chǎn)生硫化氫,并生成三氯化銻。遇明火或與強(qiáng)氧化劑接觸由于自發(fā)化學(xué)反應(yīng)而著火。與氯酸鹽、過(guò)氯酸、三氧化二鉈接觸由于自發(fā)化學(xué)反應(yīng)而爆炸。加熱分解或與酸或酸煙接觸生成硫氧化物和銻; 與水或水蒸氣反應(yīng)產(chǎn)生有毒和可燃蒸氣。

接觸機(jī)會(huì)

用于顏料、玻璃、火柴、炸藥、煙火等的生產(chǎn)。在生產(chǎn)與使用過(guò)程中易接觸。

國(guó)內(nèi)主要生產(chǎn)廠商:湖南冷水灘市錫礦山

侵入途徑

消化道與呼吸道。

毒理學(xué)簡(jiǎn)介

大鼠腹腔注射LDLo: 1390mg/kg。小鼠腹腔注射LD50: 209mg/kg。

參見<銻及其化合物>。

臨床表現(xiàn)

參見<銻及其化合物>與<三氯化銻>。

美國(guó)HSDB引用文獻(xiàn)：

*Chronic poisoning from handling antimony sulfide /from mining/ in Morocco has been reported. Symptoms ... /included/ headache, muscular pains, vertigo, anorexia, and altered blood makeup. [R17, 1514]

*Workmen in a plant where antimony trisulfide was used in the manufacture of grinding wheels were studied. This study focused on cardiovascular status, since prior to the study there had been six sudden deaths in a group of 125 workers exposed to antimony for 8 months to 2 years. The deaths were suspected to be due to heart disease. In the workers studied, 14 of 113 had blood pressures that were >140/90 mm Hg, and 37 of 75 showed significant changes in their EKGs, mostly the T-wave. Ulcers were detected in 7 of 111 exposed persons (63 per 1,000) as compared with 15 per 1,000 in the total plant population. No other disorders suspected of being related to antimony exposure were observed. Although use of antimony trisulfide was discontinued, EKG changes persisted in 12 of 665 workers subsequently reexamined. [R18]

*SYMPTOMATOLOGY: A. SUBACUTE POISONING 1. IRRITANT ACTIONS. EYES: PAINFUL CONJUNCTIVITIS, PHOTOPHOBIA, LACRIMATION, & CORNEAL OPACITY. RESP TRACT: RHINITIS WITH ANOSMIA, TRACHEOBRONCHITIS ... PULMONARY EDEMA WITH DYSPNEA, SOMETIMES LATE BRONCHOPNEUMONIA. SKIN: DIRECT CONTACT (AS SOLN) MAY PRODUCE ERYTHEMA & PAIN. /SULFIDE/ [R19,p. III-201]

*SYMPTOMATOLOGY: A. SUBACUTE ... 2. GI EFFECTS: PROFUSE SALIVATION, NAUSEA, VOMITING, DIARRHEA. 3. CENTRAL NERVOUS EFFECTS: GIDDINESS, HEADA